Slay the Spire

Slay the Spire Beginner Guide — 5 Habits That Win Your First Runs

Most first runs in Slay the Spire end because of a few repeated habits: taking every card, keeping all the Strikes, walking into elites too early or too late, and meeting the Act boss with a deck that cannot answer it. This guide starts with the five habits that fix most of that, then explains how a run is built (Acts, map nodes, Act 4 keys), how to build a deck, how to read intents, how to path each Act, and what every elite and boss punishes.

Slay the Spire Ascension Guide — All 20 Levels, A20 and the Heart

Ascension adds one penalty per level, from more elites at A1 to two Act 3 bosses at A20, and every penalty stays on as you climb. This guide lists all 20 modifiers with how much each one actually matters, explains the thresholds that change how you play (A5, A10, A11, A14, A15–A16, A17–A19 and A20), what has to change in your drafting, pathing and potion use, tips for each character, and the numbers for Act 4 and the Corrupt Heart at high Ascension.

Slay the Spire Relic Tier List — Every Boss Relic and When to Take It

The relic choice that decides the most runs is the boss relic: you get one pick from three after the Act 1 boss and one after the Act 2 boss, and most of the strongest options come with a real downside. This guide ranks all 30 boss relics, gives a take-or-skip rule for each one, then covers the best common, uncommon, rare and shop relics, every character-specific relic, where relics come from, and Neow's starting options.

Slay the Spire Character Guide — All Four Characters and Recommended Builds

Slay the Spire has four characters, and each one changes how a run works: the Ironclad scales Strength and Exhaust, the Silent wins with poison, Shivs and card cycling, the Defect builds orbs with Focus, and the Watcher swaps between Wrath and Calm. This guide compares all four in one table, then covers each character's starting deck, main archetypes with the key cards, what to pick and skip early, which boss relics suit them, the common mistakes, and which character to play next.